Successful Treatment of a Patient With Epstein-Barr Virus–Positive B-Cell Lymphoproliferative Disorder Resembling Post-Transplant Lymphoproliferative Disorder Using Single-Agent Rituximab
نویسندگان
چکیده
منابع مشابه
Successful treatment of Rituximab-resistant Epstein-Barr virus-associated post-transplant lymphoproliferative disorder using R-CHOP.
Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disorder (EBV-PTLD) is a complication of hematopoietic stem cell transplantation (HSCT). Standard initial treatment of patients with EBV-PTLD includes administration of rituximab or dose reduction of a calcineurin inhibitor. We report successful chemotherapeutic treatment of rituximab-resistant EBV-PTLD after HSCT in a pati...
متن کاملEpstein-Barr virus-associated post-transplant lymphoproliferative disorder.
We describe a patient that developed Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disorders (PTLD), which presented as interstitial pneumonia. He had received allogeneic bone marrow transplantation for the treatment of acute myeloid leukemia 17 months before, when he developed hypoxemia requiring emergent admission. Chest computed tomography revealed pulmonary interst...
متن کاملPost-transplant lymphoproliferative disorder.
BACKGROUND Posttransplant lymphoproliferative disorder (PTLD) is increasingly recognized as a serious complication of solid organ transplantation in both children and adults. Factors associated with increased risk of PTLD include mismatch of recipient and donor EBV serologic status (seronegative recipient with seropositive donor), and intensive drug-induced immunosuppression. METHODS AND RESU...
متن کاملEBV-reactivation and post-transplant lymphoproliferative disorder treated with rituximab.
We read the recent paper on profile of EBV-associated infectious mononucleosis (IM) by Balasubramanian, et al. [1] with interest. They concluded that EBV associated IM is more common in preschool children. Here we highlight another dreaded complication due to reactivation of EBV post-allogeneic stem cell transplant (SCT) leading to post-transplant lymphoproliferative disorder (PTLD). Mortality ...
متن کاملOcular post-transplant lymphoproliferative disorder
We report a case of an iris tumor with muttonfat keratic precipitates in a young patient after liver transplantation surgery. A 6yearold girl underwent liver transplantation for congenital biliary atresia and was subsequently immunosuppressed with oral cyclosporine. We examined her 5 years after transplantation because of a "white nodule in her left eye," which had been detected by her father o...
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ژورنال
عنوان ژورنال: Journal of Clinical Oncology
سال: 2011
ISSN: 0732-183X,1527-7755
DOI: 10.1200/jco.2011.34.8656